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The study identified 15 macroalgal species across the three study sites. Dasan Ujung Beach exhibited the highest level of species diversity, whereas Pink Beach showed the lowest diversity due to the dominance of Ulva lactuca<\/em> which was associated with eutrophic environmental conditions.<\/p>\n\n\n\n In terms of bioactive compounds, Halimeda opuntia<\/em> exhibited the highest total phenolic content, while Dictyota dichotoma<\/em> contained the highest total flavonoid content. In anticancer activity assays, the extract of Ulva reticulata<\/em> was the most effective in inhibiting MCF-7 breast cancer cells, whereas the petroleum ether and ethyl acetate fractions of Dictyota dichotoma<\/em> demonstrated the strongest activity against HT-29 colorectal cancer cells.<\/p>\n\n\n\n \u201cThe anticancer potential of these brown macroalgae is highly promising. However, further research is needed to isolate their active compounds in order to achieve greater selectivity against cancer cells,\u201d said Abdullah.<\/p>\n\n\n\n Gas chromatography\u2013mass spectrometry (GC\u2013MS) analysis also identified several major bioactive compounds in Dictyota dichotoma<\/em> that are believed to contribute to its anticancer activity.<\/p>\n\n\n\n <\/p>\n\n\n\n Abdullah noted that the study demonstrates the importance of conserving coastal ecosystems not only for preserving biodiversity, but also for supporting the sustainable utilization of marine resources in the development of natural product-based medicines.<\/p>\n\n\n\n \u201cIndonesia\u2019s marine biodiversity holds tremendous potential for innovation in the health sector. Therefore, conservation efforts and scientific research must continue to advance hand in hand,\u201d said Abdullah.<\/p>\n\n\n\n Macroalgae are known to produce secondary metabolites as a defense mechanism against environmental stress and predation. Previous studies have demonstrated that these compounds possess a wide range of biological activities, including antioxidant, immunomodulatory, and anticancer properties.<\/p>\n\n\n\n Although West Nusa Tenggara is home to a rich diversity of macroalgae, research on their anticancer potential has largely focused on red macroalgae. Abdullah\u2019s study broadens this scope by investigating green and brown macroalgae, two groups that have received relatively little scientific attention to date.<\/p>\n\n\n\n The doctoral promotion examination was chaired by the Dean of FMIPA UI, Prof. Dr. Tito Latif Indra, M.Si. The findings of this research are expected to serve as a reference for the development of anticancer drug candidates based on Indonesia\u2019s marine biodiversity through further studies on active compounds that are safer and more selective.<\/p>\n\n\n\n <\/p>","protected":false},"excerpt":{"rendered":" Depok, 15 Juli 2026 \u2014 Penelitian terhadap makroalga hijau dan cokelat dari perairan Nusa Tenggara Barat membuka peluang baru dalam pengembangan bahan alam sebagai kandidat obat antikanker. Selain memetakan kondisi ekologi makroalga di Lombok Timur, riset tersebut juga mengidentifikasi senyawa bioaktif yang berpotensi menghambat pertumbuhan sel kanker. Temuan itu dipaparkan Abdullah Rasyid dalam sidang promosi […]<\/p>\n","protected":false},"author":1,"featured_media":18379,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,194],"tags":[],"class_list":["post-18378","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-berita","category-mipa-update"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"yoast_head":"\n![\"\"](\"https:\/\/biologi.sci-ui.id\/wp-content\/uploads\/2026\/07\/sci-770.jpg\")
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