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The Department of Biology
Faculty of Mathematics and Natural Sciences Universitas Indonesia
OSPACE
Research > Research Group > OSPACE
Research Group of Omic Science, Physiology, and Chemical Ecology (RG OSPACE)
The Omic Science, Physiology, and Chemical Ecology Research Group (RG OSPACE) is dedicated to advancing integrative biological research that bridges molecular, physiological, and ecological perspectives. Our work spans the exploration of biodiversity across various ecosystems, the application of omic technologies (including genomics, transcriptomics, proteomics, and metabolomics), and the study of chemical ecology to understand interactions within and between species.
We investigate how organisms respond to abiotic environmental factors and pursue applied research on natural products with promising therapeutic, agricultural, and environmental value. By combining cutting-edge molecular techniques with ecological insight, we aim to generate impactful knowledge that supports sustainable development and biodiversity conservation.
Research Focus:
- Exploration of biodiversity across various ecosystems.
- Application of omic sciences (genomics, transcriptomics, proteomics, metabolomics) in diverse organisms.
- Study of chemical ecology and interspecies interactions.
- Investigation of organismal responses to abiotic environmental factors.
- Applied research on natural products for therapeutic, agricultural, and environmental applications.
Aims:
To advance high-quality research and innovation, mentor undergraduate and graduate students, and foster both local and international research collaborations in the fields of omic science, physiology, and chemical ecology. Our ultimate goal is to translate scientific findings into real-world applications that enhance human well-being and promote ecological balance.
Competence and Research Focus Area:
Expertise in biodiversity, chemodiversity, and their applied uses in ecology, conservation, and natural product development. His research emphasizes the exploration of species and chemical diversity in various ecosystems, and how these can be harnessed for environmental sustainability and human benefit.
Ratna Yuniati
Expertise in plant ecophysiology and ethnobiology, with a strong research focus on the physiological responses of plants to biotic and abiotic stresses, as well as the influence of environmental and genetic factors on the expression of functional metabolites. Her interdisciplinary research explores the intersection of plant-environment interactions and traditional ecological knowledge, particularly in the context of local plant use, conservation, and sustainability.
Expertise in male reproductive physiology, with a research focus on the potential of natural products to enhance or inhibit male reproductive function, particularly in relation to sperm quality. Her work primarily involves in vivo studies using mice to assess physiological impacts at multiple levels. Additionally, she utilizes both in vivo and in vitro assays as essential tools to evaluate the effects of natural compounds and to explore the underlying biological mechanisms involved.
Expertise in plant physiology, bionanotechnology, and bioprospecting, with a focus on exploring bioactive metabolites from plants and their responses to environmental factors. Through an interdisciplinary approach, she develops plant-based nanomaterials and investigates their applications in various sectors, including health (e.g., as antimicrobial agents and in toxicity studies), agriculture (e.g., as natural growth enhancers, nanofertilizers, and nanopesticides), and environmental sustainability (e.g., as eco-friendly solutions for pollution control and resource management).
Expertise in plant–microbe interactions, plant diversity, metabolomics, and molecular physiology. Her research also focuses on the applied aspects of these fields, including how plant-associated microbes and metabolite profiles contribute to plant health, resilience, and productivity. Through an integrative approach, she explores the molecular and ecological dynamics that underpin plant-microbe relationships and their potential applications in sustainable agriculture and environmental management
Oriza Savitri Ariantie
Expertise in semen cryoconservation using both chemical and natural products for both ruminant animals and fish, with a strong focus on the development of natural product-based semen diluents. Her research explores innovative formulations for both liquid and frozen semen diluents, aiming to enhance sperm viability and preservation across a wide range of animal species. The work supports advancements in reproductive biotechnology and sustainable animal breeding programs
Expertise in plant development through in vitro fertilization systems, with a strong focus on chromosomal structure and behavior, including the use of Fluorescence In Situ Hybridization (FISH) to study genome organization and dynamics. Her research also encompasses molecular plant breeding and crop improvement, utilizing plant bioinformatics to analyze genomic data and support breeding strategies. To broaden the impact and interdisciplinary relevance of her work, she is actively exploring plant metabolomics to understand the biochemical and physiological effects of genetic and developmental modifications in plants.
Cluster Research Chemodiversity and Reproductive Biotechnology (Yasman, Upi Chairun Nisa, Oriza Savitri Ariantie):
This cluster centers on the chemical diversity of natural products and their physiological impacts, particularly in the context of reproductive health and conservation. It combines chemodiversity, male reproductive physiology, and cryopreservation research to develop practical biotechnological innovations for both human and animal systems.
Key Themes:
- Chemodiversity and natural product applications
- Reproductive physiology and sperm quality
- Semen cryopreservation and diluent formulation
- Functional applications of plant-based compounds in reproductive biotechnology
Research Cluster Plant Systems, Omics, and Environmental Interaction (Ratna Yuniati, Windri Handayani, Niarsi Merry Hemelda, Tety Maryenti):
This cluster focuses on understanding plant biology through the lens of omics technologies, physiology, and environmental interaction. It integrates ecophysiology, plant development, metabolomics, and plant–microbe relationships to explore plant adaptation, diversity, and responses to biotic and abiotic factors. Applications span agriculture, environmental sustainability, and plant biotechnology.
Key Themes:
- Plant physiology and development
- Omic approaches (metabolomics, molecular physiology, plant bioinformatics)
- Plant–environment and plant–microbe interactions
- Biodiversity and ecosystem response
- Applications in agriculture, health, and sustainability